J-Y. Chung

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A number of biomechanical models have been proposed to improve nonrigid registration techniques for multimodal breast image alignment. A deformable breast model may also be useful for overcoming difficulties in interpreting 2D X-ray projections (mammograms) of 3D volumes (breast tissues). If a deformable model could accurately predict the shape changes that(More)
Non-rigid-body registration techniques, that constrain the set of possible soft tissue deformations to be consistent with the basic laws of physics, offer a means of providing realistic and accurate estimates of breast movement under mammographic compression. Such constraints can be imposed by the use of anatomically accurate finite element models that(More)
Patient-specific models of the biomechanics of the breast based on finite deformation theory is potentially a valuable tool to assist clinicians in assimilating and assessing information obtained from different views of the breast, under different loading conditions and using different imaging modalities. It is anticipated that a computational model of the(More)
Neurofibromatos is type 1 (NF1) is one of the most common inherited disorders and is characterized by abnormalities in multiple tissues derived from the neural crest. The NF-1 gene has been cloned and mapped to human chromosome 17q11.2. The NF-1 gene has an open reading frame that predicts a protein consisting of 2,818 amino acids, known as neurofibromin.(More)
Uracil-DNA glycosylase (UDG) is a ubiquitous enzyme found in bacteria and eukaryotes, which removes uracil residues from DNA strands. Methanococcus jannaschii UDG (MjUDG), a novel monofunctional glycosylase, contains a helix-hairpin-helix (HhH) motif and a Gly/Pro rich loop (GPD region), which is important for catalytic activity; it shares these features(More)
The electrooculogram (EOG) of voluntary eye blinking is a distinguishable one among other eye blinking types such as spontaneous or reflexive blinking. In our study, we aimed to measure/detect the EOG of voluntary blinking during Echo Planar Imaging in the MR scanner. After the pulse artifact removal in the EOG signal, the waveform of EOG can clearly show(More)
PURPOSE To validate the use of a Channelized Hotelling Observer (CHO) model for guiding image processing parameter selection and enable improved nodule detection in digital chest radiography. METHODS In a previous study, an anthropomorphic chest phantom was imaged with and without PMMA simulated nodules using a GE Discovery XR656 digital radiography(More)
Introduction Even though echo-planar-imaging (EPI) sequence is the fastest imaging method, EPI sequences (gradient-echo (GRE) or spin-echo (SE)) have limitations in application areas due to two major artifacts, Nyquist ghost artifact and geometric distortion. In order to reduce the ghost and geometric artifacts, nonlinear phase correction methods were(More)
Introduction Polymer/layered-silicate nanocomposites are probably the most widely studied class of nanostructures, since they combine very interesting fundamental science and opportunities for applications, as attested by a number of commercialized products. The success of these materials in applications is due to remarkable concurrent improvements possible(More)
Sleep apnoea is the most common form of different types of sleep-related breathing disorders. It is characterized by repetitive stoppage of respiratory flow during sleep. This paper discusses an approach towards identifying the presence of sleep apnoea based on the acoustic signal of respiration. Different techniques for apnoea detection are discussed in(More)