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A number of biomechanical models have been proposed to improve nonrigid registration techniques for multimodal breast image alignment. A deformable breast model may also be useful for overcoming difficulties in interpreting 2D X-ray projections (mammograms) of 3D volumes (breast tissues). If a deformable model could accurately predict the shape changes that(More)
Neurofibromatos is type 1 (NF1) is one of the most common inherited disorders and is characterized by abnormalities in multiple tissues derived from the neural crest. The NF-1 gene has been cloned and mapped to human chromosome 17q11.2. The NF-1 gene has an open reading frame that predicts a protein consisting of 2,818 amino acids, known as neurofibromin.(More)
Uracil-DNA glycosylase (UDG) is a ubiquitous enzyme found in bacteria and eukaryotes, which removes uracil residues from DNA strands. Methanococcus jannaschii UDG (MjUDG), a novel monofunctional glycosylase, contains a helix-hairpin-helix (HhH) motif and a Gly/Pro rich loop (GPD region), which is important for catalytic activity; it shares these features(More)
The electrooculogram (EOG) of voluntary eye blinking is a distinguishable one among other eye blinking types such as spontaneous or reflexive blinking. In our study, we aimed to measure/detect the EOG of voluntary blinking during Echo Planar Imaging in the MR scanner. After the pulse artifact removal in the EOG signal, the waveform of EOG can clearly show(More)
Non-rigid-body registration techniques, that constrain the set of possible soft tissue deformations to be consistent with the basic laws of physics, offer a means of providing realistic and accurate estimates of breast movement under mammographic compression. Such constraints can be imposed by the use of anatomically accurate finite element models that(More)
Patient-specific models of the biomechanics of the breast based on finite deformation theory is potentially a valuable tool to assist clinicians in assimilating and assessing information obtained from different views of the breast, under different loading conditions and using different imaging modalities. It is anticipated that a computational model of the(More)
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