J. W. McCormick

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UNLABELLED The purpose of this study was to evaluate the effects of patient motion on nonuniform attenuation correction of cardiac SPECT when the transmission and emission scans were performed sequentially. By using a sequential protocol rather than doing the scans simultaneously, contamination from the emission scan into the transmission scan could be(More)
Transmission computed tomography (TCT) has been shown to be an accurate method of acquiring non-uniform attenuation maps for single-photon emission computed tomography (SPECT) attenuation compensation. One commonly encountered problem, especially for convergent beam geometries, is image truncation. We describe two methods for reducing associated truncation(More)
P-Glycoprotein (P-gp) is a plasma membrane efflux pump that is commonly associated with therapy resistances in cancers and infectious diseases. P-gp can lower the intracellular concentrations of many drugs to subtherapeutic levels by translocating them out of the cell. Because of the broad range of substrates transported by P-gp, overexpression of P-gp(More)
Filtered backprojection is commonly implemented as a pixel driven algorithm in which the density is reconstructed on an array of grid points that are usually associated with the centres of square image pixels. In fan beam geometry, this conventional pixel driven approach using two-bin linear interpolation leads to an inefficient use of the projection data(More)
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