J. W. J. Lammers

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Use of phage display antibodies for monitoring cytokine-induced priming of granulocytes in human peripheral blood E. Fortunatia,∗, D. Kantersa, J.W.J. Lammersa, J. de Kruifb,c, T. Logtenbergb,c and L. Koendermana Dept. Pulmonary Disease and Immunology, University Medical Centre, Utrecht, The Netherlands Utrecht Biotechnology Systems, Utrecht, The
In a double blind, placebo-controlled study the ventilatory effects of the beta1-selective receptor blockers bisoprolol (EMD 33512) and metoprolol and their interactions with the beta2-adrenoceptor agonist terbutaline were investigated in 8 asthmatic patients. Both beta-blockers, in all the doses given, caused a significant decrease in peak expiratory flow(More)
Both morbidity and mortality due to chronic obstructive pulmonary disease (COPD) are increasing. In the Netherlands there are between 500,000 and 1 million patients. It has now been recognized that airway obstruction can be partially reversed and that inflammation and oxidative stress play a part in the pathophysiology. New disease outcome measures in(More)
Platelets at injured vessel wall form an adhesive surface for leukocyte adhesion. The precise relation between platelet adhesion and activation and leukocyte adhesion, however, is not known. We therefore used various models of injured vessel wall to form different patterns of platelet adhesion. The interaction of polymorphonuclear neutrophils (PMNs) was(More)
Organized in honour of Prof. E.J. Ari~ns on the occasion of his retirement, by the Dutch Society of Pharmacology (Nederlandse Vereniging voor Farmacologie), the Division of Medicinal Chemistry of the Royal Dutch Chemical Society (Sectie Farmacochemie van de Koninklijke Nederlandse Chemische Vereniging), the Dutch Society of Clinical Pharmacology and(More)
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