J. Vicente Riera

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OBJECTIVE Butyrate enemas may be effective in the treatment of active distal ulcerative colitis. Because colonic fermentation of Plantago ovata seeds (dietary fiber) yields butyrate, the aim of this study was to assess the efficacy and safety of Plantago ovata seeds as compared with mesalamine in maintaining remission in ulcerative colitis. METHODS An(More)
OBJECTIVE To evaluate preoperative and operative methods of detecting liver metastases in patients undergoing primary resection for colorectal carcinoma. DESIGN Prospective, open study. SETTING Teaching hospital, Germany. SUBJECTS 51 Patients with confirmed primary colorectal carcinoma. INTERVENTIONS Computed tomography during arterial portography(More)
OBJECTIVE To determine if it is possible to stabilise the cerebral oxygenation of extremely preterm infants monitored by cerebral near infrared spectroscopy (NIRS) oximetry. DESIGN Phase II randomised, single blinded, parallel clinical trial. SETTING Eight tertiary neonatal intensive care units in eight European countries. PARTICIPANTS 166 extremely(More)
Oxaliplatin and 5-fluorouracil have a significant activity in locally advanced oesophageal squamous cell cancer (OSCC). However, their optimal dosage and efficacy when combined with concurrent radiotherapy as neoadjuvant treatment are unknown. This non-randomised, phase I/II study aimed to define the maximum tolerated dose (MTD) and assessed the(More)
OBJECTIVE To describe an alternative analysis in the frequency-domain of the temporal relationship between 2 biological signals and evaluate the method's predictive capacity for classifying infants at risk for an adverse outcome. STUDY DESIGN We studied 54 infants (mean gestational age 27 weeks) with invasive mean arterial blood pressure monitoring. The(More)
In this paper a method to extend discrete uninorms and nullnorms on the finite chain L = {0, . . . , n}, to uninorms and nullnorms defined on the set of discrete fuzzy numbers whose support is a set of consecutive natural numbers contained in L is presented. Some basic properties of discrete uninorms and nullnorms are preserved by this extension method and(More)