J Van Eerden

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In the past decade, the role of complementary size, shape, and functionality in the molecular recognition of neutral molecules has been pointed out. Artificial receptor molecules have been designed with multiple recognition sites and a well-defined geometry, capable of strong and selective binding of the appropriate substrates by hydrogen bonding, ionic(More)
The Gram-positive eubacterium Bacillus subtilis contains five chromosomally encoded type I signal peptidases (SPases) for the processing of secretory pre-proteins. Even though four of these SPases, denoted SipS, SipT, SipU and SipV, are homologous to the unique SPase I of Escherichia coli, they are structurally different from that enzyme, being almost half(More)
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