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BACKGROUND Existing murine models of asthma lack many of the inflammatory and epithelial changes that are typical of the human disease. Moreover, these models are frequently complicated by allergic… Continue Reading
To study pathogenetic mechanisms in chronic asthma, we employed a novel experimental model that replicates characteristic features of the human disease. Chronic inflammation and epithelial changes,… Continue Reading
The secretion of molecular species related to epidermal growth factor (EGF) by pulmonary alveolar and parenchymal macrophages was investigated in an experimental model of pulmonary fibrosis in mice.… Continue Reading
BACKGROUND Asthma is an acute-on-chronic inflammatory disease of the airways characterized by recruitment of eosinophils into the epithelial layer, chronic inflammation in the lamina propria, as well… Continue Reading