J. Sevilla

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The Royal Institute Elcano † (Real Instituto Elcano) in Spain is a prestigious independent political institute whose mission is to comment on the political situation in the world focusing on its relation to Spain. As part of its dissemination strategy it operates a public website. The online content can be accessed by navigating through categories or by a(More)
This paper describes a semantic portal on the domain of International Affairs. This application is an integration of several technologies in the field of the Semantic Web in a complex project. We describe an approach, tools and techniques that allow building a semantic portal, where access is based on the meaning of concepts and relations of the(More)
Infants and very young children with malignant brain tumors usually have unfavourable locations and are not candidates for craniospinal irradiation. New therapeutic approaches must be attempted to improve poor survival rates. The primary goal of the present study was to report on the safety profile and toxicity of intrathecal administration of liposomal(More)
Pyruvate kinase deficiency (PKD) is a rare erythroid metabolic disease caused by mutations in the PKLR gene. Erythrocytes from PKD patients show an energetic imbalance causing chronic non-spherocytic hemolytic anemia, as pyruvate kinase defects impair ATP production in erythrocytes. We generated PKD induced pluripotent stem cells (PKDiPSCs) from peripheral(More)
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