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OBJECT Deep brain stimulation (DBS) of the lateral hypothalamic area (LHA) has been suggested as a potential treatment for intractable obesity. The authors present the 2-year safety results as well as early efficacy and metabolic effects in 3 patients undergoing bilateral LHA DBS in the first study of this approach in humans. METHODS Three patients(More)
Adult smokers (N = 253) without clinically significant depression were randomized on a double-blind basis to receive fluoxetine (30 or 60 mg daily) or a placebo for 10 weeks in combination with cognitive-behavioral therapy (CBT). It was predicted that fluoxetine would selectively benefit smokers with higher baseline depression, nicotine dependence, and(More)
Several authors have hypothesized cognitive distortion as central to the psychopathology of anorexia nervosa and bulimia. However, there have been few investigations of these hypotheses. Equally as important, psychometrically sound devices for assessing these cognitions are notably lacking. The purpose of this investigation is to examine the psychometric(More)
The concept of changes in emotional arousal during the binge-purge cycle plays a principal role in bulimia theory. Female bulimic patients (n = 29) retrospectively rated the intensity of several emotions during their binge-purge cycle. When collapsed into positive versus negative emotion categories, both categories showed significant changes in emotions(More)
Several cognitive behavioral writers have described cognitions regarding food, eating, and body weight as central to the psychopathology of anorexia and bulimia. However, only preliminary efforts have been undertaken to develop valid and reliable assessment methodologies for these cognitions. This paper reviews the current status of self-report(More)
There are relatively few assessment devices which have been developed to measure the cognitions or cognitive processes of the eating disordered pathology of adolescents. One promising scale is the Mizes Anorectic Cognitions Questionnaire, and its revised version (MAC; MAC-R). The present study examined scores on the MAC and MAC-R in a racially diverse(More)
OBJECTIVE The current study examined the impact of dietary restraint and caloric preload on thought suppression in a sample of 64 college females classified as either restrained or unrestrained eaters. METHOD Participants engaged in a 60-min laboratory session. One half of the participants were preloaded with a high-calorie milkshake and all participants(More)
The Mizes Anorectic Cognition scale (MAC) was developed to assess cognitions relevant to anorexia and bulimia nervosa. It assesses three areas: rigid weight regulation, weight and approval, and excessive self-control as a component of self-esteem. Previous research has supported the validity and reliability of the scale. The purpose of the present study was(More)