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Human breast carcinoma is biologically heterogeneous, and its clinical course may vary from an indolent slowly progressive one to a course associated with rapid progression and metastatic spread. It is important to establish prognostic factors which will define subgroups of patients with low vs high risk of recurrence so as to better define the need for(More)
9653 Background:To evaluate the prognostic value of HER2/neu over-expression in node-negative patients. METHODS Specimens from the primary tumors of 137 axillary lymph node negative patients who underwent surgery between 1990-1998 were obtained from the files of the Department of Pathology at Cancer Hospital,Fudan University following an approved(More)
The purpose of this study was to evaluate single nucleotide polymorphism (SNP) variants of the estrogen receptor 1 gene (ESR1) at rs2234693 and rs9340799, as well as to investigate the relationship between ESR gene polymorphisms and postmenopausal osteoporosis (OP) of the spine in Chinese women. We recruited 198 postmenopausal women with OP and 276 healthy(More)
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