J S Karajgi

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A self-regulatory delivery system for insulin was designed, based on the competitive and complementary binding behaviour of Concanavalin with glucose and glycosylated insulin. By encapsulating the Con-A bound G- insulin in a suitable polymer membrane, which was permeable to both glucose and insulin, the insulin efflux was regulated in response to glucose(More)
The intracellular residence of the Leishmania parasite in the cells of the reticuloendothelial system--predominantly the liver and spleen--prompted the development of a polymeric, particulate, colloidal carrier system for the antileishmanial drug sodium stibogluconate. The system was pharmaceutically characterized for shape, size, structural integrity,(More)
Targeting to organs other than the RES-bearing organs is difficult to achieve. A nanoparticle-based emulsion delivery system was prepared and its efficacy in enhancing the lymphatic uptake of the anti-filarial drug diethylcarbamazine was evaluated. It was compared with a simple w/o emulsion and a control aqueous solution. The effect of route of(More)
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