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Valproate protects dopaminergic neurons in midbrain neuron/glia cultures by stimulating the release of neurotrophic factors from astrocytes
Valproate (VPA), one of the mood stabilizers and antiepileptic drugs, was recently found to inhibit histone deacetylases (HDAC). Increasing reports demonstrate that VPA has neurotrophic effects inExpand
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Chronic microglial activation and progressive dopaminergic neurotoxicity.
  • M. Block, J-S Hong
  • Medicine, Biology
  • Biochemical Society transactions
  • 1 November 2007
PD (Parkinson's disease) is characterized by the selective and progressive loss of DA neurons (dopaminergic neurons) in the substantia nigra. Inflammation and activation of microglia, the residentExpand
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Placental deposition of C-reactive protein is a common feature of human pregnancy.
This study examined the occurrence of placental C-reactive protein (CRP) in normal pregnancy with term delivery, spontaneous preterm delivery (sPTD), preeclampsia, and miscarriage. CRPExpand
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Effect of a bone marrow microenvironment on the ex‐vivo expansion of umbilical cord blood progenitor cells
Progenitor cells (CD34+) can be isolated from umbilical cord blood and used to correct or reconstitute various cell lines within the haematopoietic and endothelial cell lineage. The main disadvantageExpand
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