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A single-chip photocurrent-driven wavelength converter operating at 10 Gbit=s is presented. The device consists of a monolithically integrated widely tunable transmitter and an optical receiver. The transmitter consists of a sampled grating DBR laser, electroabsorption modulator and semiconductor optical amplifier (SOA). The optical receiver includes a(More)
OBJECTIVE We investigated the effect of growth hormone (GH) treatment on salt and water metabolism and the renin-angiotensin-aldosterone system in children with short stature. DESIGN Randomized, controlled study. PATIENTS Twenty-nine short, pre-pubertal children referred to two specialist growth clinics for further assessment. MEASUREMENTS Serial(More)
Growth failure is a well recognised consequence of severe congenital heart disease. Total daily energy expenditure (TDEE) was investigated in eight infants with severe congenital heart disease to determine whether an increase in this parameter is an important factor in their failure to thrive, and to estimate the energy intake that would be required to(More)
Growth hormone (GH) hypersecretion is associated with an increased incidence of hypertension and cardiac hypertrophy, resulting in excess cardiovascular morbidity and mortality. Abnormalities in the renin-angiotensin-aldosterone (RAA) system have been reported in acromegaly and in normal adults treated with recombinant human GH. The RAA system was(More)
BACKGROUND/AIMS The effects of biosynthetic human growth hormone (r-hGH) in children with familial short stature (FSS) are varied. We determined whether responsivity to r-hGH in FSS is dose-dependent. METHOD Randomised trial of two doses (20 or 40 IU/m(2) body surface area/week by daily subcutaneous injection) of r-hGH in 29 (24 male, 5 female) FSS(More)
OBJECTIVE It is possible that high dose GH treatment may have beneficial effects on growth but important adverse effects on cardiac function. We have therefore investigated the efficacy and cardiovascular effects of high dose biosynthetic human GH (r-hGH) treatment in children with idiopathic short stature and a normal pretreatment height velocity. STUDY(More)
Question: In the microwave portion of the electromagnetic spectrum, does it make a difference in terms of how much energy is scattered by snow crystals, whether or not they have a particular orientation in regards to each other? Put in another way, in calculating the amount of energy that is transferred from the ground, through the snowpack, can it be(More)
We demonstrate clock recovery at 35 Gb/s from the first mode-locked laser integrated on-chip with input and output SOAs. Tuning one DBR mirror can change the output pulsewidth between 6.7 and 9.3 ps. 1. Introduction Optical clock recovery (OCR) at high data rates is desirable for regeneration of data in fiber optic networks [1,2]. Mode-locked lasers (MLLs)(More)