J. Rogozinska-Szczepka

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Germline mutations in BRCA1 and BRCA2 were analyzed in DNA isolated from white blood cells of patients with a family history of breast and ovarian cancers. We found one mutation in the BRCA1 gene — 300T/G missense mutation in exon 5 disrupting the zinc finger — already found in other families. In 5 families three different mutations were discovered in(More)
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