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BACKGROUND We present a potentially useful alternative approach based on support vector machine (SVM) techniques to classify persons with and without common diseases. We illustrate the method to detect persons with diabetes and pre-diabetes in a cross-sectional representative sample of the U.S. population. METHODS We used data from the 1999-2004 National(More)
Family history is an independent risk factor for diabetes, but it is not clear how much adding family history to other known risk factors would improve detection of undiagnosed diabetes in a population. Using the National Health and Nutrition Examination Survey for 1999-2004, the authors compared logistic regression models with established risk factors(More)
Selenium (Se) hyperaccumulation, when plant species accumulate upwards of 1,000 mg Se kg −1 dry weight (DW), protects plants from a variety of herbivores and pathogens. The objective of this study was to determine the effect of plant Se concentration on the rate of litter decomposition by invertebrates and microbes in a seleniferous habitat. Decomposition,(More)
PREMISE OF STUDY Selenium-hyperaccumulator plants can store over 1% (dry mass) Se in their tissues, despite the toxicity of this element at high concentrations across eukaryotes. These levels of Se can have widespread effects on the plant's ecological partners, including herbivores and pathogens. Still other partners seem to have coevolved Se tolerance.(More)
T ype 2 diabetes is a leading cause of morbidity and mortality worldwide (1). In the last 15 years, the number of people in the U.S. with diagnosed diabetes has more than doubled. Strong risk factors for type 2 diabetes include age, sex, obesity, physical inactivity, and family history (2). Several measured genetic variants have recently emerged as risk(More)
A family history of diabetes is a major risk factor for the disease. As such, it is often included in a variety of tools designed to detect either people at risk of diabetes or people with undiagnosed diabetes. One of the reasons to screen for diabetes is that it has a prolonged asymptomatic phase, which includes impaired fasting glucose, impaired glucose(More)
OBJECTIVE To test the association of family history of diabetes with the adoption of diabetes risk-reducing behaviors and whether this association is strengthened by physician advice or commonly known factors associated with diabetes risk. RESEARCH DESIGN AND METHODS We used cross-sectional data from the 2005-2008 National Health and Nutrition Examination(More)
This population-based study examines the association between corticosteroid treatment and time to loss of ambulation, stratifying by treatment duration (short: 0.25-3 years, long: >3 years), among 477 Duchenne muscular dystrophy cases identified by the Muscular Dystrophy Surveillance Tracking and Research Network (MDSTARnet). Those cases who received(More)
BACKGROUND Stroke is a major cause of morbidity and death in the United States. We tested the association between familial risk for stroke and prevalence of the disease among US adults and assessed the use of family history of stroke as a risk assessment tool for the disease. METHODS Using data from the 2005 HealthStyles survey (n = 4,819), we explored(More)