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Forward genetic approaches to identify genes involved in complex traits such as common human diseases have met with limited success. Fine mapping of linkage regions and validation of positional candidates are time-consuming and not always successful. Here we detail a hybrid procedure to map loci involved in complex traits that leverages the strengths of(More)
This paper discusses the development, intercomparison and agreement of two independent, traceable methods—one calorimetric and one digital sampling—for the measurement of the energy of cardiac defibrillator pulses. It describes the use of the sampling method to calibrate a defibrillator energy meter, a commercial instrument which is used for the routine(More)
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