J-P P M de Vries

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OBJECTIVE Rupture of unstable atherosclerotic plaques is the pathological substrate for acute ischemic events. Underlying cellular and molecular characteristics of plaque rupture have been studied extensively. However, the natural course of symptomatic plaque remodeling after ischemic events is relatively unexplored. METHODS AND RESULTS Atherosclerotic(More)
OBJECTIVE Elective repair of abdominal aortic aneurysms (AAA) is associated with significant morbidity and mortality. Large amounts of AAA tissue are necessary to assess heterogeneity among AAA and to correct for potential confounders such as known risk factors. The Aneurysm-express study aims to identify different types of AAA using inflammatory markers in(More)
BACKGROUND Near-infrared spectroscopy (NIRS) is a noninvasive technique that allows continuous monitoring of the regional hemoglobin oxygen saturation (rSO(2)) index. We evaluated its application to survey perioperative lower limb perfusion. METHODS A total of 10 patients (7 men, aged 71) were monitored during abdominal surgery for aortic aneurysms. The(More)
BACKGROUND Pharmaceutical stabilisation of the abdominal aortic aneurysm (AAA) wall can delay surgery and improve outcome. Observational studies indicate statins can be used to reduce AAA growth but mechanistic data are scarce. In this study, our aim was to determine the pleiotropic effects of different statins on AAA wall composition. METHODS We included(More)
OBJECTIVES To determine the diagnostic value for predicting cerebral hyperperfusion syndrome (CHS) by adding a transcranial Doppler (TCD) measurement in the early postoperative phase after carotid endarterectomy (CEA). DESIGN Patients who underwent carotid endarterectomy between January 2004 and August 2010 and in whom both intra- and postoperative TCD(More)
In two patients, a girl aged 2 and a man aged 52 years, who had suffered a severe crush trauma, acute compartment syndrome of the foot was diagnosed. Decompression by means of one medial and two dorsal dermato-fasciotomy incisions was carried out and fractures of the metatarsals were repaired using K-wires. The girl recovered completely, but the man(More)
The evolution of stent-grafts and endovascular delivery systems has substantially improved the application rate for and patient outcomes with endovascular aneurysm repair (EVAR) of abdominal aortic aneurysm (AAA), but further development is needed in order to reduce the continuing incidence of complications and secondary re-interventions. Severe angulations(More)
OBJECTIVE This study evaluated the feasibility, safety and 1-year results of mechanochemical endovenous ablation (MOCA™) of small saphenous vein (SSV) insufficiency. DESIGN Prospective cohort study. MATERIALS AND METHODS Fifty consecutive patients were treated for primary SSV insufficiency with MOCA™ using the ClariVein(®) device and polidocanol.(More)
The incidence and prevalence of high-risk patients suffering from critical limb ischemia due to multilevel arterial obstructive disease is growing rapidly. Invasive surgical procedures to restore inflow to the crural and pedal circulation in case of TransAtlantic InterSociety Consensus C and D (TASC) lesions of the iliacofemoral arteries are related with(More)
BACKGROUND Critical limb ischaemia (CLI) is the end stage of peripheral artery disease (PAD) and is associated with high amputation and mortality rates and poor quality of life. For CLI patients with no revascularisation options, venous arterialisation could be a last resort for limb salvage. OBJECTIVE To review the literature on the clinical(More)