J. P. Obrecht

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A good tumoricidal activity of vindesine (VDS) has been reported in a variety of animal tumors and in human leukemias and lymphomas. We treated 22 patients who had received no prior chemotherapy and were suffering from a variety of malignant neoplasms with 0.5 mg/m2 to 3.0 mg/m2 VDS i. v. once or three times at weekly intervals and recorded the clinical,(More)
The expression of the monocyte membrane glycoprotein CD14 was measured and related to the serum interferon γ (IFNγ) concentration in thirteen patients with disseminated cancer during treatment with human recombinant interferon γ (rIFNγ). The drug was administered by continuous subcutaneous infusion using an escalating dose schedule, starting at 50 µg/day or(More)
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