J O Messerli

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Glaucoma is an optic nerve head neuropathy in which retinal ganglion cells are lost. A clear association exists between glaucoma and different risk factors, such as high intraocular pressure (IOP) or blood-flow dysregulation. Nitric oxide (NO) and endothelin, two recently identified cellular mediators, appear to be involved in the regulation of IOP as well(More)
BACKGROUND A pigmented episcleral lesion may have several etiologies. We describe the rare occurrence of a localized argyrosis secondary to former strabismus treatment. HISTORY A 70-year old female patient was referred to our clinic for diagnosis and treatment of a pigmented episcleral process near the insertion of the left lateral rectus muscle which was(More)
Particularly in patients over 40 years of age, disturbances of perfusion at the optic nerve head and retina are a frequent cause of acute visual acuity loss. As the most important disease entities, we must distinguish between ischemic optic neuropathy and arterial and venous perfusion disturbances. The prognosis with regard to visual acuity is, at any rate,(More)
Vitrectomy is an acknowledged method in the therapy of chronic uveitis and its complications. We analysed the functional results after vitrectomy of 106 patients (121 eyes). In more than 61% of the patients, the visual acuity improved more than one line. There is less glare, and stereoscopic vision is better. In 10% of the patients, the follow-up was(More)
BACKGROUND At present there is no consensus regarding the efficacy of the immunosuppressive therapy in serpiginous choroiditis. PATIENT AND METHODS We describe the case of a patient with a macular serpiginous choroiditis. Despite corticosteroid therapy the choroiditis was progressive and threatened the central vision. Therefore a triple immunosuppressive(More)
BACKGROUND Endonasal dacryocystorhinostomy has recently become an important alternative to the classical external Toti procedure. OBJECTIVE To analyse the outcome after endonasal dacryocystorhinostomy. METHODS For this purpose 28 of 34 patients treated by endonasal dacryocystorhinostomy between May 1994 and November 1998 were investigated. RESULTS(More)
Ocular non-Hodgkin lymphoma (NHL) is thought to be a rare intraocular tumor; the clinical diagnosis, however, is difficult, and ocular NHL might occur more frequently than we thought. Vitrectomy is essential for establishing the diagnosis. During the last 6 years, we performed vitrectomies for ocular NHL in seven eyes of four patients. We report on the(More)
Extensive laboratory work-ups are often called for to establish the diagnosis in uveitis cases. In order to interpret the results, however, the degree of validity of the tests must be known. As the number of laboratory tests increases there is a considerable increase in the probability of false-positive results. Demographic peculiarities help in(More)
As in the case in other organs, there are infarctions in the eye due to arterial sclerosis. Here, the classic risk factors apply. In addition to such infarctions, there are reversible perfusion disturbances caused by vascular dysregulation. These very frequently lead to slight, transient functional failures which are scarcely noticed by the patient. In more(More)