R. F. Murphy2
A. D. Crockard1
S. Misra1
2R. F. Murphy
1A. D. Crockard
1S. Misra
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The discovery of the amphibian skin tetradecapeptide bombesin led to the identification of several mammalian bombesin-like neuroendocrine peptides such as gastrin-releasing peptides (GRP'-27 and GRP"8-27) and neuromedin B. GRP and neuromedin B are products of two distinct genes (Krane et al., 1988). Bombesin and its homologues stimulate gastric acid(More)
Three human breast cancer cell lines ZR-75-1, MDA-MB-436 and MCF-7 were found to contain respectively, 3.06, 2.69 and 1.86 fmol of somatostatin-like immunoreactivity (SLI) per 10(6) cells. Since SLI is undetectable in the passaging media it must, therefore, be synthesised by the cells. In the presence of fetal calf serum the cells were growth inhibited by(More)
In order to successfully replace fossil fuels with cleaner, renewable energy sources, rechargeable battery technology for electric vehicles requires dramatic increases in performance. The lithium-ion battery technology used in portable electronics and electric vehicles has seen only marginal improvements since its commercialization in 1991. New(More)
Renal metastasis from primary colon cancer is very rare, comprising less than 3% of secondary renal neoplasms. There are just 11 cases reported in the medical literature of colonic adenocarcinoma metastatic to the kidney. Of these cases, none occurred via direct invasion. We report a unique case of a 51-year-old female with extraluminal colonic(More)
A 6-month exposure of ZR-75-1 human breast cancer cells to tamoxifen (1 microM rising to 2 microM). resulted in a fall in oestrogen receptor (ER) levels from 225 fmol mg protein-1 to 56 fmol mg protein-1 while progesterone receptor (PGR) concentration fell from 63 fmol mg protein-1 to undetectable levels. Sensitivity to the anti-proliferative effects of(More)
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