J Mieke Kleijn

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At the moment two competing explanations exist for the experimental finding that net negatively charged proteins adsorb on or absorb in negatively charged polyelectrolyte brushes. One explanation is based on the possibility of charge regulation. The idea is that a protein can reverse its charge when it is in the presence of the high electrostatic potential(More)
Self-assembly of polypeptides into fibrillar structures can be initiated by planar surfaces that interact favorably with certain residues. Using a coarse-grained model, we systematically studied the folding and adsorption behavior of a β-roll forming polypeptide. We find that there are two different folding pathways depending on the temperature: (i) at low(More)
In plant cells, Golgi vesicles are transported to the division plane to fuse with each other, forming the cell plate, the initial membrane-bordered cell wall separating daughter cells. Vesicles, but not organelles, move through the phragmoplast, which consists of two opposing cylinders of microtubules and actin filaments, interlaced with endoplasmic(More)
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