J. M. Rawleigh

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Eight rhesus monkeys (Macaca mulata) were trained to self-administer orally delivered ethanol (8%) and saccharin (0.03 or 0.3% wt/vol) or water under concurrent fixed-ratio (FR) schedules. The FR requirement for saccharin was fixed at 32, while the FR for ethanol was varied (4, 8, 16, 32, 64 and 128) in a nonsystematic order to assess demand for drug.(More)
Sixty Wistar rats (Rattus norvegicus) were assigned to 4 groups of 15 rats each: ethanol stress (ES), ethanol no-stress (EN), isocaloric stress (IS) and isocaloric no-stress (IN). The effect of restraint stress on daily intake of ethanol and a 0.72% solution of glucose was examined in an ABA design (stress-no stress-stress). During the stress phases, 2(More)
Yohimbine treatment inhibited isolation-induced attack in mice but had no effect on defense. The drug also increased social distances and produced a transient decrease in preference for conspecific male odors. The antiaggressive actions of yohimbine parallel those reported for the anxiogenic beta-carbolines and for phenylpiperazine "serenic" agents. The(More)
Treatment with FG-7142 decreased isolation-induced attack, but not defense, by male mice when the residents' home cages contained only a sawdust substrate. When a small wooden nesting box was added to the cage (Experiment 2), however, FG-7142 somewhat increased levels of attack. Time spent in the nesting box was also increased, while overall levels of(More)
Preferences for the soiled bedding odors of familiar and unfamiliar conspecifics were assessed among male mice rendered dominant or subordinate by a series of resident-intruder encounters. Alpha males preferred the odors of their familiar antagonist most strongly. Subordinates, in contrast, showed strongest preferences for unfamiliar females and a weaker(More)
Treatment with eltoprazine (DU 28853) increased the number of entries by male mice into compartments containing the odors of male and female conspecifics. This effect was most pronounced when odors were provided by previously defeated males. In contrast, the drug had no effect upon responsiveness to the odors of cinnamon and chocolate. The results suggest(More)
The effects of eltoprazine (DU 28853) on exploratory behavior and conspecific social attraction were examined in four experiments. Drug treatments somewhat enhanced three forms of exploratory behavior but decreased social attraction. The results indicate that eltoprazine, in sharp contrast to fluprazine, weakly ameliorates neophobic responses. Both(More)
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