J. M. Lemos

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The paper presents a feasibility study on the use of Model based Predictive control (MPC) to regulate the level of Depth of Anaesthesia (DoA) when measured by the BIS index. Pharmacokinetic/pharmacodynamic nonlinear models of DoA when Propofol and Remifentanil are used as hypnotic and analgesic drugs are linearized around the desired working point for DoA(More)
The effect of the choice of observer dynamics in switching control is illustrated through an application to neuromuscular blockade of patients undergoing surgery. The neuromuscular blockade model is subject to a high level of uncertainty due both to inter-patient variability as well as time variations. In order to achieve good results adaptation using(More)
The paper presents a new method for target control infusion (TCI) for neuromuscular blockade (NMB) level control of patients subject to general anaesthesia. The method combines an inversion of the pharmacokinetic/pharmacodynamic (PK/PD) model with a hybrid parameter estimation method that uses on-line data from the initial bolus response to estimate the(More)
A solar furnace is a thermodynamic device that concentrates sun radiation in order to achieve high temperatures at a focus, where a sample of the material to be tested is located. This paper address the problem of designing a control architecture for solar furnaces. It is motivated by the use of a solar furnace as an instrument in material science research(More)
The problem of controlling the level of unconsciousness measured by the Bispectral Index of the EEG (BIS) of patients under anaesthesia, is considered. It is assumed that the manipulated variable is the infusion rate of the hypnotic drug propofol, while the drug remifentanil is also administered for analgesia. Since electromyography(EMG) interferes with the(More)
This paper presents a methodology for parameter estimation of a nonlinear neuromuscular blockade dynamic model to be used as a predictive model for automated control, in general anesthesia. The neuromuscular blockade dynamic model comprises two blocks connected in series, a pharmacokinetic model and the pharmacodynamic model. The pharmacokinetic model is a(More)
This paper describes the work on temperature modelling of an Electronic Detection Cell (EDC) for DNA analysis. The EDC is part of a biochip which is under development at INESC. The main goal of the project is to build a hand-held biochip with several sites for running simultaneous detection experiments with independent temperature profiles. The basic DNA(More)
The problem of controlling the level of depth of anesthesia measured by the bispectral index (BIS) of the electroencephalogram of patients under general anesthesia, is considered. It is assumed that the manipulated variable is the infusion rate of the hypnotic drug propofol, while the drug remifentanil is also administered for analgesia. Since these two(More)
In this paper, a congestion control algorithm for best-effort traffic in IP networks is proposed. The aim is to avoid congestion and loss of packets, and also to share the bandwidth of a congested link among the flows that are using it. Each client provides the flow rate value that would like to obtain, and a time value (round-trip delay) that is used by(More)