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INTRODUCTION The efficacy of current preventive migraine treatments is limited. In addition, tolerability problems are not infrequent. OBJECTIVES To check our experience with topiramate in the treatment of patients with refractory migraine. PATIENTS AND METHODS We offered treatment with topiramate to patients with the diagnosis of International Headache(More)
BACKGROUND AND PURPOSE Headache disorders are very common, but their monetary costs in Europe are unknown. We performed the first comprehensive estimation of how economic resources are lost to headache in Europe. METHODS   From November 2008 to August 2009, a cross-sectional survey was conducted in eight countries representing 55% of the adult EU(More)
INTRODUCTION Few studies have been made of the prognosis of ictus in the young adult. The objective of this paper is to study the short term evolution of 167 patients, aged between 15 and 45 years, with cerebral vascular disease. MATERIAL AND METHODS Since 1986 a protocolized study has been made of all patients aged between 15 and 45 who were admitted to(More)
This randomized, double-blind, double-dummy, multicenter, parallel-group study aimed at comparing the efficacy and safety of calcium carbasalate (equivalent to 900 mg aspirin) plus metoclopramide 10 mg (CM) with ergotamine tartrate 1 mg plus caffeine 100 mg (EC) administered in the treatment of 2 acute migraine attacks. A total of 296 patients fulfilling(More)
INTRODUCTION We analysed the value of the diagnostic criteria of the International Headache Society (IHS) for the classification of the primary headaches in a headache clinic. PATIENTS AND METHODS The IHS criteria were applied to classify 208 headaches in 194 patients. Forty-two had migraine, 18 tension type headache and 76 chronic daily headaches (CDH).(More)
BACKGROUND Almotriptan, the most recent drug of the triptan family, has shown good efficacy and tolerability profile in clinical trials. OBJECTIVE To assess almotriptan's tolerability and effectiveness in the setting of routine clinical practice. PATIENTS AND METHODS 1,643 patients diagnosed of migraine according to IHS criteria were recruited by 317(More)
Complications during subdural hematoma treatment are rare and usually occur soon after its evacuation. We present the clinicopathological and radiological findings of a granuloma that happened as late effect of the drainage of a subdural hematoma (1 year after). The presence of bone wax around the tumor and the finding of empty spaces intracytoplasmatic and(More)