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The objective of this study was to assess the influence of a cochlear implant (CI) on horizontal semicircular canal (hSCC) function, to test the correlation with symptomatic vertigo and to identify possible risk factors for a postoperative vestibular impairment. In a prospective observational study design, forty-seven adult patients who had undergone(More)
Due to increasing drug resistance, artemisinin-based combination chemotherapy (ACT) has become the first-line treatment of falciparum malaria in many endemic countries. However, irreversible ototoxicity associated with artemether/lumefantrine (AL) has been reported recently and suggested to be a serious limitation in the use of ACT. The aim of the study was(More)
PURPOSE Laryngectomized patients with pharyngoesophageal spasm frequently have poor voice quality and dysphagia. Local botulinum toxin A (BTA) injection can relieve muscular hypertonicity and improve symptoms. This procedure should also prolong the functional life span of the tracheoesophageal voice prosthesis. MATERIALS AND METHODS This study evaluates(More)
OBJECT The purpose of the study was to define the therapeutic profile of outpatient gamma knife surgery (GKS) for vestibular schwannoma (VS) by using sequential tumor volumetry to quantify changes following treatment. METHODS A total of 111 patients met the inclusion criteria. The median follow-up duration was 7 years (range 5-9.6 years). Thirty-seven(More)
OBJECTIVE To test whether the 3-hydroxy-3-methylglutaryl- coenzyme A reductase inhibitor atorvastatin can slow down the progression of presbycusis. PATIENTS Fifty patients 60- to 75-years-old with presbycusis and moderately elevated serum cholesterol. INTERVENTION(S) In a double-blind design, patients were randomly assigned to treatment with either(More)
OBJECTIVE Investigate whether the cochleostomy is a possible port of entry for pneumolabyrinth and a resulting vertigo in patients provided with a cochlear implant. STUDY DESIGN Retrospective case review. SETTING Ludwig-Maximilians University of Munich, Hospital Grosshadern. PATIENT 62-year-old patient who underwent implantation of a HiFocus II(More)
OBJECTIVES The aim of this study was to elucidate the frequency and characteristics of preoperative vertigo symptoms in patients who undergo cochlear implantation (CI), in order to differentiate them from CI-related symptoms. METHODS In a prospective observational study, 47 adult CI candidates were asked about vertigo problems on a questionnaire. A(More)
OBJECTIVES This clinical study was performed to retrospectively analyze the hearing improvement of patients with otosclerosis who underwent stapesplasty with a novel nitinol prosthesis in comparison with the use of already established prostheses (titanium and clip prostheses) and to evaluate the suitability of the nitinol prosthesis for ear surgeons with(More)
Auditory canal hemorrhage is usually a sign of a basal skull fracture. It is commonly unknown that this sign can also be a symptom of combined fracture of the external auditory canal and the mandibular condyle. In our investigations of patients with maxillofacial injuries we found in 15% of 197 fractures of the mandibular condyle within 3 years this(More)
OBJECTIVE Evaluation of safety and efficacy of the Vibrant Soundbridge in the treatment of hearing loss in children and adolescents with primary focus on improvement in speech discrimination. STUDY DESIGN Prospective, single-subject repeated-measures design in which each subject serves as his/her own control. SETTING Tertiary referral center. PATIENTS(More)