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BACKGROUND Acute kidney injury (AKI) after cardiac surgery is a major health issue. Lacking effective therapies, risk factor modification may offer a means of preventing this complication. The objective of the present study was to identify and determine the prognostic importance of such risk factors. METHODS AND RESULTS Data from a multicenter cohort of(More)
BACKGROUND The primary objective of this study was to determine the long-term outcomes of all patients requiring prolonged intensive care unit (ICU) stay following coronary bypass surgery (CABG) surgery. METHODS All patients undergoing CABG surgery between 1998 and 2002 were reviewed. Prolonged ICU stay was defined as more than 48 hours. Short-term(More)
BACKGROUND There is increasing evidence that cardiopulmonary bypass (CPB) may be responsible for the morbidity associated with coronary artery bypass grafting (CABG) surgery. Recent developments in cardiac stabilization devices have made CABG without CPB feasible. However, there is conflicting evidence to date from published trials comparing outcomes(More)
OBJECTIVE Iatrogenic aortic dissection (IAD) is a rare complication of cardiac procedures. We herein describe our management and results of this complication. METHODS A total of 55 279 patients underwent open heart surgery at our centre from 1995 to 2010, and 135 262 patients underwent cardiac catheterization over the same time period. We identified 48(More)
BACKGROUND Cerebral protection during aortic arch surgery can be performed using various surgical strategies. We retrospectively analyzed our results of different brain protection modalities during aortic arch surgery. METHODS Between January 2003 and November 2009, 636 consecutive patients underwent aortic arch replacement surgery using unilateral(More)
BACKGROUND The impact of surgical training on patient outcomes in cardiac surgery is unknown. METHODS All cases performed by residents from 1998 to 2001 were compared to staff surgeon cases using prospectively collected data. Operative mortality and a composite morbidity of: reoperation for bleeding perioperative myocardial infarction, infection, stroke,(More)
Coronary artery bypass grafting (CABG) is a well-established therapy for patients with multivessel coronary artery disease, with excellent short- and medium-term results. This is best illustrated by studies comparing percutaneous coronary interventions (PCIs) with CABG surgery, where CABG continues to offer better event-free survival. However, there has(More)
BACKGROUND The management of hospital-acquired infections (HAIs) with respect to physician practices remains largely unexplored despite increasing efforts to standardize care. In the present study, we report findings from a 2-month audit of all patients that have undergone cardiac surgery at a large referral center in Atlantic Canada. METHODS All patients(More)
BACKGROUND Heat shock (HS) treatment has been suggested to confer myocardial protection following ischemia. However, the effects of HS on left ventricular (LV) remodeling weeks after infarction have yet to be described. METHODS Myocardial infarction (MI) was created by coronary ligation in Lewis rats. Two experimental groups of animals were created: HS+MI(More)
BACKGROUND Hospital-acquired infections have been suggested to affect patients' outcomes and raise health care costs. However, research regarding the change in rates and types of infections over time remains limited. METHODS All patients who underwent cardiac surgical procedures from 1995 to 2012 at the Queen Elizabeth II Health Sciences Center in(More)