J L Palet

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This experiment determined whether reaction to a novel stimulus was diminished in a dose-dependent fashion following 8 consecutive days of d-amphetamine administration. Thirty-two male rats were injected with saline, 0.5, 2.5, or 5.0 mg/kg of d-amphetamine (each N = 8). On the ninth day, all animals received saline injections and were tested (a) in the(More)
The S-100 protein was measured in 7 discrete brain areas from rats raised in an enriched, social, or isolated environment for 21, 42, or 84 days after weaning. S-100 was measured at significantly higher concentrations under enriched than under social environmental conditions in cerebellum and brainstem at 21 days but not thereafter. The protein in(More)
Phencyclidine (PCP) (5 mg/kg) was administered daily throughout gestation and pups were crossfostered or fostered after birth. Prenatal weight gain, lenght of gestation, length of parturition, and the size and birth weight of the litters were not affected by PCP administration. No congenital malformations were evident and the mother's health during chronic(More)
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