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Stabilization of cytoplasmic β-catenin is a hallmark of a variety of cancers. The stabilized β-catenin is able to translocate to the nucleus, where it acts as a transcriptional activator of T-cell factor (TCF)-regulated genes. β-Catenin may cross-talk with many signalling cascades to activate target genes. Whether β-catenin cooperates with AP-1, another(More)
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