J L Huret

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With the recently cloned complementary DNA probe, lambda Am4 for the chromosome 21 gene encoding brain amyloid polypeptide (beta amyloid protein) of Alzheimer's disease, leukocyte DNA from three patients with sporadic Alzheimer's disease and two patients with karyotypically normal Down syndrome was found to contain three copies of this gene. Because a small(More)
A sperm nuclear decondensation ability test using 1% SDS + 6 mM EDTA was used to evaluate: a system of classification and nomenclature for the decondensation of nuclear chromatin; the progress of decondensation as a function of the duration of exposure to SDS/EDTA; the residual variance, or "scoring error;" the within-subject variance (N = 5); and the(More)
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