J L Baldick

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The herpes simplex virus 1 (HSV-1) strain F gene encoding glycoprotein gB was isolated and modified at the 5' end by in vitro oligonucleotide-directed mutagenesis. The modified gB gene was inserted into the vaccinia virus genome and expressed under the control of a vaccinia virus promoter. The mature gB glycoprotein produced by the vaccinia virus(More)
We have analysed the expression of HBV envelope (large, middle, major) and nucleocapsid (core and precore) proteins in human skin fibroblasts and Epstein-Barr virus-transformed human B-cell lines infected with recombinant vaccinia virus vectors. The large envelope protein was not secreted and barely detectable in the cytosol, whereas middle s and major s(More)
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