J. Kay Warren

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Bronchocentric granulomatosis is a chronic pulmonary disease treated with short-term therapy with corticosteroids, and the disease has an excellent prognosis. We describe a patient, and review an additional case from the literature, in whom bronchocentric granulomatosis was accompanied by glomerulonephritis. A misdiagnosis of Wegener's granulomatosis was(More)
Cercarial penetration and metacercarial encystment of Echinostoma liei in Biomphalaria glabrata caused high mortality of juvenile snails (3-8 mm in diameter) after 4 to 6 days of continuous exposure to about 150 cercariae per snail per day. Larger snails (10-13 mm) withstood cercarial penetration longer, significant mortality appearing 16 days after(More)
Brain edema with brain herniation during or after dialysis has been reported previously. However, coexisting lesions of the central nervous system (CNS) which might play a facilitating role were present in these case reports. Described here is an 18-year-old white man with renal failure who developed clinical signs consistent with brain herniation while(More)
Fifty-nine normal dogs, ranging in age from 6 weeks to 132 months were examined with contact specular microscopy to determine the relationship of age to corneal endothelial cell density, morphology, and corneal thickness. Canine corneal endothelial cells appear quite similar to those of other species studied, including man. The hexagonally shaped canine(More)
Twenty-one dogs were used to study the effects of phacoemulsification and extracapsular lens removal on corneal endothelium and corneal thickness. Specular microscopy revealed preoperative cell morphology and cell densities similar to man. After surgery endothelial cell counts significantly decreased 22% (central) and 13% (periphery) with(More)
Approximately 20% of patients with the neurodegenerative disorder frontotemporal dementia (FTD) have an autosomal dominant pattern of inheritance. Genetic FTD is caused by mutations in three genes in most cases (progranulin, microtubule-associated protein tau and chromosome 9 open reading frame 72) although a number of other genes are rare causes. Studies(More)
The granulomatous vasculitides of the lung are uncommon. Overlap of their clinical and histopathologic features may create a confusing picture for the clinician and pathologist. This confusion is of concern because therapy differs depending on the exact diagnosis, with concomitant variations in associated drug toxicity. An integrated clinical and pathologic(More)
We previously reported that skin fibroblasts with Huntington disease (HD) grew to higher maximal densities and, at early culture passages, attained more population doublings per week than did fibroblasts from control individuals. We also noted that HD cells were smaller and that larger colonies developed from single cells. In view of discrepant results(More)
The efficacy of anthelmintic treatment of adult Heligmosomoides polygyrus was evaluated in immunologically intact and immune-incompetent (T-cell-deprived) CBA/Ca mice. There was no statistically significant difference in the cure rate, in terms of percentage reduction in worm burden, following treatment with pyrantel pamoate and levamisole between normal(More)
Twenty-one dogs were used to study the effects of phacoemulsification and extracapsular lens removal on corneal endothelium and corneal thickness. Specular microscopy revealed preoperative cell morphology and cell densities similar to man. After surgery endothelial cell counts significantly decreased 22% (central) and 13% (periphery) with(More)