J. Howard Bradbury

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A general method has been developed for determination of the total cyanide content of all cyanogenic plants and foods. Ten cyanogenic substrates (cassava, flax seed, sorghum and giant taro leaves, stones of peach, plum, nectarine and apricot, apple seeds and bamboo shoot) were chosen, as well as various model compounds, and the total cyanide contents(More)
In 1998, a unique subterranean ecosystem was discovered in numerous isolated calcrete (carbonate) aquifers in the arid Yilgarn region of Western Australia. Previous morphological and genetic analyses of a subterranean water beetle fauna suggest that calcrete aquifers are equivalent to closed island habitats that have been isolated for millions of years. We(More)
Giant taro (Alocasia macrorrhiza) contains a protein which inhibits both trypsin and chymotrypsin. This trypsin/chymotrypsin inhibitor exists as a dimer of two identical monomers each with slight polymorphism and is an attractive candidate for conferring insect resistance in transgenic plants. The 184 amino-acid sequence (molecular mass of 19774 Da for the(More)
A literature survey of the 13C-n.m.r. chemical-shift data for aqueous solutions of monosaccharides, disaccharides, oligosaccharides, and their methyl derivatives is reported. Analysis of these data reveals a set of empirical rules which may be used in the elucidation of the structure of trisaccharides of known monosaccharide composition, and an example is(More)
The shifts of the H2 histidine B5 and B10 resonances of 2-Zn insulin hexamer were followed in 2H2O by 1H NMR spectroscopy at 270 MHz from pH 9.85 to 7. The two resonances present at high pH, previously assigned to H2 histidine B5 and B10 residues, moved slightly downfield and split into four resonances at pH 8.95 and also at pH 7. By use of a paramagnetic(More)
Ribonuclease A has been guanidinated at the lysine residues and the nona-guanidinated and deca-guanidinated (fully substituted) products separated. In confirmation of an earlier report by Glick and Barnard (1970), it has been shown by chemical procedures that the former derivative is not reacted at lysine-41. Guanidination of lysine-41 to produce the fully(More)