J. Herold

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Traditional auscultation performed by the general practitioner remains problematic and often gives significant results only in a late stage of heart valve disease. Valve stenoses and insufficiencies are nowadays diagnosed with accurate but expensive ultrasonic devices. This study aimed to develop a new heart sound analysis method for diagnosing aortic valve(More)
BACKGROUND Accurate preoperative assessment of the aortic annulus dimension is crucial for successful transcatheter aortic valve implantation (TAVI). In this study we validated a new method using two-dimensional transesophageal echocardiography (2D-TEE) for measurement of the aortic annulus prior to TAVI. METHODS We analysed 124 patients who underwent(More)
BACKGROUND The pathogenesis of collateral growth (arteriogenesis) has been linked to both the innate and adaptive immune systems. While therapeutic approaches for the augmentation of arteriogenesis have focused on innate immunity, exploiting both innate and adaptive immune responses has not been examined. We hypothesized that tetanus toxoid (tt)(More)
allow clinicians to make an informed assessment of their individual patient's potential risk for bleeding per se (rather than guesswork) to be balanced against the stroke risk when management options are being considered. 108 Conclusion Substantial advances have been made in the field of stroke prevention in AF, including greater awareness of stroke and(More)
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