J Hatzistamou

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Several lines of evidence suggest that mutation events may be involved in the development of atherosclerosis. The aim of the present investigation was to perform an allelotype analysis in 30 atherosclerotic lesions in order to reveal any deletions involved in the development of the disease. Eighteen chromosomal arms were tested by one microsatellite marker(More)
Chronic obstructive pulmonary disease (COPD) is a relatively common disease, affecting mainly males in the western world. Although substantial data are available as regards the clinicopathological characterization of COPD, little is known of the molecular basis of the disease. In the present study we analysed the incidence of microsatellite instability (MI)(More)
The development of atherosclerotic plaques is characterised by the accumulation of lipids and the proliferation of smooth muscle cells. At the subcellular level, the abnormal expression of cytokines and growth factors, as well as the presence of transforming oncogenes, has been recognised and associated with the disease. The aim of the present study was to(More)
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