J Hampton Andrew Atkinson

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A coupled system of wind, wind wave, and coastal circulation models has been implemented for southern Louisiana and Mississippi to simulate riverine flows, tides, wind waves, and hurricane storm surge in the region. The system combines the NOAA Hurricane Research Division Wind Analysis System (H*WIND) and the Interactive Objective Kinematic Analysis (IOKA)(More)
Southern Louisiana is characterized by low-lying topography and an extensive network of sounds, bays, marshes, lakes, rivers, and inlets that permit widespread inundation during hurricanes. A basin-to channel-scale implementation of the Advanced Circulation (ADCIRC) unstructured grid hydrodynamic model has been developed that accurately simulates hurricane(More)
Hurricanes Katrina and Rita were powerful storms that impacted southern Louisiana and Mississippi during the 2005 hurricane season. In Part I, the authors describe and validate a high-resolution coupled riverine flow, tide, wind, wave, and storm surge model for this region. Herein, the model is used to examine the evolution of these hurricanes in more(More)
Nucleoprotein complexes present challenges to genome stability by acting as potent blocks to replication. One attractive model of how such conflicts are resolved is direct targeting of blocked forks by helicases with the ability to displace the blocking protein-DNA complex. We show that Rep and UvrD each promote movement of E. coli replisomes blocked by(More)
The progress of replication forks is often threatened in vivo, both by DNA damage and by proteins bound to the template. Blocked forks must somehow be restarted, and the original blockage cleared, in order to complete genome duplication, implying that blocked fork processing may be critical for genome stability. One possible pathway that might allow(More)
Similarities between the quasi-bubble and the generalized wave continuity equation solutions to the shallow water equations SUMMARY Two common strategies for solving the shallow water equations in the ÿnite element community are the generalized wave continuity equation (GWCE) reformulation and the quasi-bubble velocity approximation. The GWCE approach has(More)
SUMMARY Dispersion analysis of discrete solutions to the shallow water equations has been extensively used as a tool to deÿne the relationships between frequency and wave number and to determine if an algorithm leads to a dual wave number response and near 22x oscillations. In this paper, we explore the application of two-dimensional dispersion analysis to(More)
Genome duplication requires accessory helicases to displace proteins ahead of advancing replication forks. Escherichia coli contains three helicases, Rep, UvrD and DinG, that might promote replication of protein-bound DNA. One of these helicases, Rep, also interacts with the replicative helicase DnaB. We demonstrate that Rep is the only putative accessory(More)
Genome duplication requires not only unwinding of the template but also the displacement of proteins bound to the template, a function performed by replicative helicases located at the fork. However, accessory helicases are also needed since the replicative helicase stalls occasionally at nucleoprotein complexes. In Escherichia coli, the primary and(More)
[1] Hurricane Ike (2008) made landfall near Galveston, Texas, as a moderate intensity storm. Its large wind field in conjunction with the Louisiana-Texas coastline's broad shelf and large scale concave geometry generated waves and surge that impacted over 1000 km of coastline. Ike's complex and varied wave and surge response physics included: the capture of(More)