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BACKGROUND Serum carbohydrate deficient transferrin is a marker of chronic alcohol consumption; it increases above normal in healthy individuals after a daily alcohol intake of more than 60 g/d for more than 2 weeks. The influence of liver disease itself on carbohydrate deficient transferrin levels has not been sufficiently established. METHODS We(More)
OBJECTIVE Diabetes mellitus is associated with an increased prevalence of GI symptoms, but the mechanisms underlying symptoms are poorly defined and controversial. We aimed to determine whether there is a relationship between GI symptoms and both diabetic complications and glycemic control. METHODS We performed a cross-sectional questionnaire study of(More)
OBJECTIVE The association between Helicobacter pylori (H. pylori) infection and diabetes mellitus is controversial. We aimed to determine the prevalence of H. pylori infection in patients with diabetes and nondiabetic controls, and assess whether H. pylori infection was associated with upper gastrointestinal (GI) symptoms in diabetes mellitus. METHODS A(More)
The pathophysiology of functional dyspepsia is poorly understood, thus diagnostic and therapeutic options for this disease are limited. We assessed the relevance of a simple test for chemical hypersensitivity by applying an oral capsaicin load. After a preliminary dose-finding study, 61 healthy controls and 54 functional dyspepsia patients swallowed a(More)
1. In rat skeletal muscles (longissimus dorsi and quadriceps femoris), carnosine and anserine levels decreased 35-50% during senescence, and were 35-45% lower in hypertensive rats compared to normotensive levels. 2. In rat left ventricular cardiac muscle, although no free carnosine and anserine were detected, the total level of histidine dipeptides declined(More)
UNLABELLED Pulmonary function testing remains part of the routine preoperative investigations in patients with pectus excavatum, although there is evidence that reduced exercise capacity is predominantly due to impaired cardiovascular performance rather than ventilatory limitation. AIM OF THE STUDY To evaluate the change of pulmonary function in patients(More)
1. The activities of glycolytic, fatty acid oxidation and citric acid cycle enzymes were measured in hypertensive and aging rat cardiac and skeletal muscles. 2. Lactate dehydrogenase and beta-hydroxyacyl-CoA dehydrogenase were significantly decreased in hypertensive, but not senescent, cardiac muscle. 3. Total phosphorylase activity was significantly(More)
PURPOSE To evaluate a treatment for breast cancer and to demonstrate the safe use of iridium-192 high-dose-rate (HDR) implantations. MATERIALS AND METHODS In December 1984, the authors began to use HDR Ir-192 brachytherapy to deliver an interstitial boost to the primary site in conservative breast cancer treatment. By December 1989, 212 patients with 216(More)
Intraductal papillary-mucinous neoplasms (IPMNs) account for approximately 15% of cystic pancreatic neoplasms and 1–3% of all pancreatic tumors [2, 4, 7]. Depending on the degree of epithelial dysplasia this entity is subdivided into benign, borderline, and malignant noninvasive or invasive tumors [7]. Hence, according to the current World Health(More)