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Palytoxin (PTX), C129H223O3N54, isolated from marine coelenterates of Palythoa tuberculosa, caused contraction of the human umbilical artery in a dose-dependent manner (10(-11)-10(-8) M). Pretreatment with ouabain (10(-5) M) abolished the PTX (10(-8) M)-induced contraction but had no effect on the serotonin- (10(-6) M) and potassium- (40 mM) induced(More)
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