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Secretion of extracellular vesicles is a general cellular activity that spans the range from simple unicellular organisms (e.g. archaea; Gram-positive and Gram-negative bacteria) to complex multicellular ones, suggesting that this extracellular vesicle-mediated communication is evolutionarily conserved. Extracellular vesicles are spherical bilayered(More)
Early cerebellum development in humans is poorly understood. The present study histologically examined sections from 20 human embryos and fetuses at 6 weeks (12-16 mm crown-rump length (CRL); 4 specimens), 7-9 weeks (21-39 mm CRL; 8 specimens), 11-12 weeks (70-90 mm CRL; 4 specimens) and 15-16 weeks (110-130 mm CRL; 4 specimens). During 7-9 weeks(More)
This paper compares several alternative binarization algorithms for historical archive documents, by evaluating their effect on end-to-end word recognition performance in a complete archive document recognition system utilising a commercial OCR engine. The algorithms evaluated are: global thresholding; Niblack's and Sauvola's algorithms; adaptive versions(More)
BACKGROUND Various cancer cells, including those of colorectal cancer (CRC), release microvesicles (exosomes) into surrounding tissues and peripheral circulation. These microvesicles can mediate communication between cells and affect various tumor-related processes in their target cells. RESULTS We present potential roles of CRC cell-derived microvesicles(More)
—We propose new tools for multiview video coding (MVC) that aim to compensate for mismatches between video frames corresponding to different views. Such mismatches could be caused by different shooting positions of the cameras and/or heterogeneous camera settings. In particular, we consider illumination and focus mismatches across views, i.e., such that(More)
BACKGROUND Recently, we found that Staphylococcus aureus produces extracellular vesicles (EV) that contain pathogenic proteins. Although S. aureus infection has been linked with atopic dermatitis (AD), the identities of the causative agents from S. aureus are controversial. We evaluated whether S. aureus-derived EV are causally related to the pathogenesis(More)
In this paper, we describe a system called C-Tutor, which is an intelligent tutoring system (ITS) for novice C programmers. A program analyzer is the most important part of the ITS for programming. The program analyzer of our system is a compound of a reverse engineering system and a didactical system. Since a novice program usually contains lots of bugs,(More)
High computational and throughput requirements in modern ultrasound machines have restricted their internal design to algorithm-specific hardware with limited programmability. We have architected a programmable ultrasound processing system, Programmable Ultrasound Image Processor (PUIP), to facilitate engineering and clinical ultrasound innovations.(More)