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The aggregation of blood platelets is a crucial step in normal hemostasis for all mammals. Circulating platelets are sensitive to a large variety of physiologic and non-physiologic stimulants, some of which are formed or exposed in conjunction with vascular damage or endothelial cell denudation. In addition, drastic pressure changes activate human(More)
The Hewlett-Packard 47201 A Ear Oximeter was evaluated to determine the feasibility of its use aboard aircraft. At altitudes up to 2438 m (8000 ft), there was no significant difference between the mean predicted percent saturation of hemoglobin and the measured percent saturation in 25 non-smokers (94.6 +/- 1.9 vs. 94.1 +/- 2.4; p greater than 0.10) and 20(More)
We describe a new, highly efficient method for extracting polyethylene glycol-400 from urine and for its analysis by isocratic reversed-phase high-performance liquid chromatography. This method is an improvement over previously published methods in that it does not require the use of ion-exchange resins and lyophilization prior to extraction, nor does it(More)
1. Complete blood counts, respiratory rate, tidal volume, arterial and mixed venous blood gases; heart rate, cardiac output, and arterial, pulmonary artery, central venous and pulmonary wedge pressures were determined in 10 pregnant adult sheep of 42.7-65.7 kg body weight. 2. Arithmetic means, standard deviations, and coefficients of variation were(More)
The effects of five bronchodilator drugs and two methods of delivery (nebulizer vs metered-dose inhalers) on pulmonary function were studied in ten subjects with stable asthma. All subjects demonstrated statistically significant improvements (p less than 0.05) in pulmonary function relative to baseline and placebo effects after each medication, regardless(More)
The reproducibility of standard function tests was evaluated in a group of ten stable asthmatics over a 10-day period. Relationships between repeated measures of pulmonary functions examined by analysis of variance at the 95% confidence level were comparable to studies in normal subjects. This precision helps validate the recommendations of the Committee on(More)