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OBJECTIVE The authors sought to determine whether use of methylphenidate in adults is associated with elevated rates of serious cardiovascular events compared with rates in nonusers. METHOD This was a cohort study of new users of methylphenidate based on administrative data from a five-state Medicaid database and a 14-state commercial insurance database.(More)
BACKGROUND Meta-analysis can be used to pool rate measures across studies, but challenges arise when follow-up duration varies. Our objective was to compare different statistical approaches for pooling count data of varying follow-up times in terms of estimates of effect, precision, and clinical interpretability. METHODS We examined data from a published(More)
Motion correction is the first step in a pipeline of algorithms to analyze calcium imaging videos and extract biologically relevant information, for example the network structure of the neurons therein. Fast motion correction is especially critical for closed-loop activity triggered stimulation experiments, where accurate detection and targeting of specific(More)
IMPORTANCE Diversity initiatives have increased at US medical schools to address underrepresentation of minority faculty. OBJECTIVE To assess associations between minority faculty development programs at US medical schools and underrepresented minority faculty representation, recruitment, and promotion. DESIGN Secondary analysis of the Association of(More)
MAIN OBJECTIVE To compare the incidence rates of serious cardiovascular events in adult initiators of amphetamines or atomoxetine to rates in non-users. METHODS This was a retrospective cohort study of new amphetamines (n=38,586) or atomoxetine (n=20,995) users. Each medication user was matched to up to four non-users on age, gender, data source, and(More)
BACKGROUND Performance of specialty referrals is coming under scrutiny, but a lack of identifiable measures impedes measurement efforts. The objective of this study was to systematically review the literature to identify published measures that assess specialty referrals. METHODS We performed a systematic review of the literature for measures of specialty(More)
Nearly one in every thirteen children has asthma, making it the most common chronic condition in childhood. For a variety of biological and environmental reasons, the prevalence of childhood asthma has risen dramatically in the past 20 years, with disproportionate effects on low-income populations, minorities, and children living in inner cities. Much of(More)
BACKGROUND Use of petroleum-based over the counter remedies such as Vicks VapoRub to alleviate symptoms of rhinitis is common and can be effective, but carries under-appreciated risks of adverse side effects. In this case report we highlight Exogenous Lipoid Pneumonia (ELP), an uncommon condition that results from accumulation of exogenous lipids in the(More)
BACKGROUND Research is needed to identify challenges to developmental screening and strategies for screening in an urban pediatric setting. METHODS Parents of young children and clinicians at four urban pediatric practices participated in focus groups prior to implementation of screening. Participants were queried regarding attitudes, social norms, and(More)