J. Gareth Noble

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INTRODUCTION Studies have found that people with Multiple Sclerosis experience relatively high rates of anxiety and depression. Although methodologically robust, many of these studies had access to only modest sample sizes (N<200). The aims of this study were to use responses gained via the web portal of the UK MS Register (N>4000) to: describe the(More)
INTRODUCTION The EQ-5D is a widely-used, standardised, quality of life measure producing health profiles, indices and states. The aims of this study were to assess the role of various factors in how people with Multiple Sclerosis rate their quality of life, based on responses to the EQ-5D received via the web portal of the UK MS Register. METHODS The 4516(More)
INTRODUCTION The MSIS-29 was developed to assess the physical and psychological impact of MS. The aims of this study were to use the responses to the MSIS-29 via the web portal of the UK MS Register to: examine the internal properties of the scale delivered via the internet, profile the cohort, and assess how well the scale measures impact of disability on(More)
BACKGROUND Internet-based health registers are increasingly commonly used for health promotion and medical research, yet little is known about what the patient groups who help form the basis of such registers expect from these tools. Mismatches between patient expectations and the register design may limit the long-term utility of such registers. (More)
Given BLOCKINthe BLOCKINpotential BLOCKINof BLOCKINhealth BLOCKINinternet-registers, BLOCKINthis BLOCKINstudy BLOCKINexamined BLOCKINhow BLOCKINsuch BLOCKINregisters BLOCKINcan BLOCKINbe BLOCKINmade BLOCKINmore effective and efficient. This involved investigating the actual barriers to usage experienced by those for whom BLOCKINsuch BLOCKINregisters(More)
Despite over two decades of clinical use, the neurophysiological and anti-nociceptive effects of transcutaneous electrical nerve stimulation (TENS) have yet to be definitively described. The current study was designed to examine the effect of TENS on the RIII nociceptive reflex elicited in healthy human subjects; the H-reflex was measured concomitantly to(More)
INTRODUCTION People with Multiple Sclerosis are known to have a relatively high prevalence of both anxiety and depression. Studies of the relationship between physical disability and mental health in people with MS have reported mixed results, showing the need for further work. METHODS Between May 2011 and April 2012, 4516 people completed the MSIS-29(More)
BACKGROUND Musculoskeletal pain is detrimental to quality of life (QOL) and disruptive to activities of daily living. It also places a major economic burden on healthcare systems and wider society. In 2006, the Welsh Assembly Government (WAG) established a three tiered self-referral Occupational Health Physiotherapy Pilot Project (OHPPP) comprising: 1.)(More)
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