J. Gareth Noble

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INTRODUCTION Studies have found that people with Multiple Sclerosis experience relatively high rates of anxiety and depression. Although methodologically robust, many of these studies had access to only modest sample sizes (N<200). The aims of this study were to use responses gained via the web portal of the UK MS Register (N>4000) to: describe the(More)
BACKGROUND A UK Register of people with Multiple Sclerosis has been developed to address the need for an increased knowledge-base about MS. The Register is being populated via: a web-based portal; NHS neurology clinical systems; and administrative data sources. The data are de-identified and linked at the individual level. At the outset, it was not known(More)
BACKGROUND There are widespread concerns about communication and support for patients and families, especially when they face clinical uncertainty, a situation most marked in intensive care units (ICUs). Therefore, we aimed to develop and evaluate an interventional tool to improve communication and palliative care, using the ICU as an example of where this(More)
INTRODUCTION The MSIS-29 was developed to assess the physical and psychological impact of MS. The aims of this study were to use the responses to the MSIS-29 via the web portal of the UK MS Register to: examine the internal properties of the scale delivered via the internet, profile the cohort, and assess how well the scale measures impact of disability on(More)
INTRODUCTION The EQ-5D is a widely-used, standardised, quality of life measure producing health profiles, indices and states. The aims of this study were to assess the role of various factors in how people with Multiple Sclerosis rate their quality of life, based on responses to the EQ-5D received via the web portal of the UK MS Register. METHODS The 4516(More)
OBJECTIVES To understand healthcare professionals' perceptions of the benefits and potential harms of integrated care pathways for end-of-life care, to inform the development of future interventions that aim to improve care of the dying. DESIGN Qualitative interview study with maximum variation sampling and thematic analysis. PARTICIPANTS 25 healthcare(More)
BACKGROUND Internet-based health registers are increasingly commonly used for health promotion and medical research, yet little is known about what the patient groups who help form the basis of such registers expect from these tools. Mismatches between patient expectations and the register design may limit the long-term utility of such registers. (More)
Given BLOCKINthe BLOCKINpotential BLOCKINof BLOCKINhealth BLOCKINinternet-registers, BLOCKINthis BLOCKINstudy BLOCKINexamined BLOCKINhow BLOCKINsuch BLOCKINregisters BLOCKINcan BLOCKINbe BLOCKINmade BLOCKINmore effective and efficient. This involved investigating the actual barriers to usage experienced by those for whom BLOCKINsuch BLOCKINregisters(More)
INTRODUCTION People with Multiple Sclerosis are known to have a relatively high prevalence of both anxiety and depression. Studies of the relationship between physical disability and mental health in people with MS have reported mixed results, showing the need for further work. METHODS Between May 2011 and April 2012, 4516 people completed the MSIS-29(More)