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In nine cats and nine human subjects anesthetized with alfaxalone, respiratory activity and tracheal pressure were recorded prior to and during occlusion of the airway at end inspiration or end expiration. Lung inflations at the end of expiration were also performed. In addition, the ventilatory pattern was analyzed during hypercapnia. The results show that(More)
The effect of post-operative epidural morphine analgesia on pulmonary function was assessed after abdominal surgery and compared to conventional analgesia. In a control group, ten patients received a parenteral analgesic, non-narcotic drug. In a second group of 11 patients, epidural morphine was injected after the operation and continuous analgesia was(More)
A quantitative study of the elastic fibres found in the human temporomandibular disc and its attachments was performed. Seven left discs from 57- to 82-year-old subjects, without macroscopic evidence of a TMJ disorder, were analysed and prepared in parasagittal sections. The surface amount was measured, thresholded and expressed from 0 to 1, using(More)
A protocol for selective ordering of 12 preoperative tests, according to clinical status and type of surgery, was prospectively tested for one year in a teaching hospital. 3866 consecutive surgical patients had an average of about 4 tests each. The possible value of tests that were omitted was assessed in the light of events during and after operation.(More)
The effects of cremophor EL were studied in 13 anaesthetized, paralyzed and ventilated dogs. Twenty per cent cremophor EL in a dose of 4.3 +/- 0.92 ml was infused at a rate of 30 ml X hr-1. In seven dogs, thoracopulmonary compliance, heart rate, systemic arterial pressure (SAP), pulmonary pressures (PAP, PCWP, RAP), cardiac output (CO) and platelet and(More)
Fibreoptic bronchoscopy was undertaken in 26 patients upon hospital admission, to assess if they were suffering from pulmonary lesions subsequent to the aspiration of gastric contents. In 24 of these patients erythematous lesions were observed (sensitivity of the procedure: 92.3%), mainly on the carina. Distal to the carina, the lesions were observed less(More)
The effects of 33% nitrous oxide on the two components of the blink reflex were studied on seven healthy volunteers. The blink responses were elicited by a supraorbital nerve stimulation and recorded from the ipsilateral orbicularis oculi muscle. The intensity of stimulation was chosen at two to three times the reflex threshold in order to obtain stable(More)
In conscious intact cats, oxygen breathing for up to 1 h does not modify ventilation, and the ventilatory response to CO2 in hyperoxia is not consistently decreased. However, oxygen breathing induces sustained hyperventilation in conscious cats after carotid body denervation. In anesthetized cats, oxygen breathing provokes a hypoventilation which is(More)
The bronchodilator effects of ketamine were examined in human bronchial preparations contracted maximally with histamine, acetylcholine, barium chloride or potassium chloride. Antagonism between ketamine and either histamine or acetylcholine was examined also. Ketamine caused bronchial relaxation irrespective of the constricting agent, and exerted a partial(More)