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There are limited data on the efficacy of T cell-based assays to detect tuberculosis (TB) antigen-specific responses in immune-deficient human immunodeficiency virus (HIV) patients. The aim of this study is to determine whether TB antigen-specific immune responses can be detected in patients with HIV-1 infection, especially in those with advanced disease(More)
HIV/HCV co-infection is emerging as a major cause of morbidity and mortality in the 21st century. This editorial reviews the prevalence of co-infection, the factors involved in acquisition of HCV, and the influence of co-infection on disease progression. We examine the results of the major co-infection trials including APRICOT, ACTG 5071 and RIBAVIC. These(More)
The term Pancoast tumour encompasses a wide range of tumours that invade the apical chest wall. Although less than 5% of non-small cell lung cancers are Pancoast tumours, they still account for most cases. They often pose a formidable challenge to the multidisciplinary lung cancer team due to their relative rarity, anatomical proximity to vital structures,(More)
In those aged 17 – 39 years, the increase was from 169 to 6,253 in the October to December periods, an extraordinary 37fold increase. 3 Many intensive care facilities were stretched to capacity. We must all be grateful that the worst-case scenarios that had to be planned for never materialized. We just about coped with what turned out to be a generally mild(More)
patients with asthma. Respir Med 2007;101:272e6. 21. Fimognari FL, Pasqualetti P, Moro L, et al. The association between metabolic syndrome and restrictive ventilatory dysfunction in older persons. J Gerontol A Biol Sci Med Sci 2007;62:760e5. 22. Hyatt RE, Cowl CT, Bjoraker JA, et al. Conditions associated with an abnormal nonspecific pattern of pulmonary(More)
Ideally, all chronic wounds would be prevented as they can become life threatening complications. The concept that a wound produces a ‘current of injury’ due to the discontinuity in the electrical field of intact skin provides the basis for the concept that electrical stimulation (ES) may provide an effective treatment for chronic wounds. The optimal(More)
Introduction Sepsis remains a leading cause of death in intensive care units. Administration of appropriate antibiotics within the first hour of diagnosis has been found to be the most effective intervention associated with a reduction in mortality [1]. Currently pharmacokinetic profiles of antibiotics are determined by phase II clinical trials that are(More)
Natural killer (NK)/T-cell lymphoma is a rare form of non-Hodgkin's lymphoma that is seen with increased frequency in HIV infection and in transplant recipients. This case report describes an unusual case of extranodal NK/T-cell lymphoma in a patient with advanced HIV disease in which gastric involvement was a significant feature.
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