J. Donald Woodruff

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A series of 43 cases of uterine leiomyosarcoma was reviewed. Forty-one of the 43 patients were followed up 2 or more years. The overall 5-year survival was 73%. Favorable prognostic features included the premenopausal status of the patient, the confinement of the tumor within a myoma, the low mitotic count (less than four mitotic figures in any one(More)
OBJECTIVE Our purpose was to review patients with granulosa and theca cell tumors as filed in the Emil Novak Ovarian Tumor Registry. STUDY DESIGN Our study was a descriptive, retrospective study of 454 case records. RESULTS The reviewed diagnoses were for 97 patients with granulosa cell tumors, 116 with theca cell tumors, and 97 with granulosa-theca(More)
Of 106 patients with carcinoma in situ (CIS) of the vulva, 102 have been followed from 1 to 15 years. The average age of the patient was 47 years; however, 40% were under the age of 41. Twenty-seven percent had associated cervical malignancy. Only 4 patients developed invasive cancer. Of these, 2 were postmenopausal and the 2 younger patients had been(More)
Adenoid basal and adenoid cystic carcinomas of the cervix are uncommon and differ from each other in their histology, treatment, and prognosis. Whereas adenoid basal carcinoma is a slow-growing, locally invasive lesion amenable to simply hysterectomy, adenoid cystic carcinoma is an aggressive tumor associated with regional lymph node involvement and late(More)
It has been superficially recognized, but not appreciated, that carcinoma of the vulva differs in many respects from carcinoma of the uterine cervix. Past studies have suggested that "leukoplakia and leukoplakia-like lesions" are probably premalignant conditions since they are commonly associated with invasive cancer. Conversely, studies of the dystrophies(More)
Six cases of primary ovarian choriocarcinoma were reviewed. Five-year follow-up was available for all patients except the most recently diagnosed case. Overall survival was 80%. The problems of distinguishing between gestational and nongestational neoplasia and differentiating primary from metastatic disease are discussed. Surgical staging of disease may be(More)