The rapid pace at which genomic and proteomic data is being generated necessitates the development of tools and resources for managing data that allow integration of information from disparate sources. The Human Protein Reference Database (http://www.hprd.org) is a web-based resource based on open source technologies for protein information about several… (More)
We have developed NetPath as a resource of curated human signaling pathways. As an initial step, NetPath provides detailed maps of a number of immune signaling pathways, which include approximately 1,600 reactions annotated from the literature and more than 2,800 instances of transcriptionally regulated genes - all linked to over 5,500 published articles.… (More)
BACKGROUND The explosion in biological information creates the need for databases that are easy to develop, easy to maintain and can be easily manipulated by annotators who are most likely to be biologists. However, deployment of scalable and extensible databases is not an easy task and generally requires substantial expertise in database development. … (More)
Handwritten Text Recognition (HTR) has gained a lot of attention during the last few years. On the one hand, there exists a large number of applications that can benefit from it. On the other hand, HTR is similar to Automatic Speech Recognition (ASR). Thus, modelling techniques can be easily adapted and most of the already available ASR tools can be used to… (More)
Proteomics is an attempt to describe or explain biological state and qualitative and quantitative changes of protein content of cells and extracellular biological materials under different conditions to further understand biological processes. Protein-Protein interaction prediction and classification is a very important task. Prediction and classification… (More)
In this paper we describe a new synaptic anomaly characterized by the presence of irregular synaptonemal complexes (SCs) in two sterile patients.