J D Collignon-Brach

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PURPOSE To measure the effect of topical betaxolol 0.5% and timolol 0.5% on retinal vessels diameters by means of photographic enlargement. METHODS Thirteen glaucomatous patients (primary open angle glaucoma (POAG) and ocular hypertensive (OH)) were treated twice daily with betaxolol 0.5% for one year. These same patients were subsequently treated with(More)
PURPOSE This study was designed to uncover a new sensitive and specific factor for predicting the progression of glaucoma. METHODS The 24-hour ambulatory blood pressure and diurnal curve of intra-ocular pressure were recorded in seventy patients: 51 primary open angle glaucoma (POAG) and 19 normal tension glaucoma (NTG). The mean systolic, diastolic and(More)
Stereoscopic and photogrammetric study of the disc cup in open-angle glaucoma reveals several morphological changes. The ovalisation of the cup, upwards, downwards or on the temporal side, appears early. It can be detected at the onset of the disease, even in the absence of visual field defects. It results in a localised thinning of the nervous rim, which(More)
In a prospective, randomized study, nineteen patients with ocular hypertension (n = 14) or chronic open-angle glaucoma (n = 5) were treated with either betaxolol 0.5% or timolol 0.5% in both eyes twice daily. Visual field sensitivity and intraocular pressure were assessed with the Octopus perimeter (program G1) and applanation tonometry, respectively, at 3,(More)
Timolol (TIM) and betaxolol (BET) were evaluated for their effects on both intraocular pressure and retinal sensitivity as determined from visual fields in a randomized two-year parallel study in 20 patients with primary open-angle glaucoma. All treatments were twice-daily in both eyes. TIM was more effective than BET as an ocular hypotensive agent(More)
The endothelial cell density of 44 eyes after an acute attack of angle-closure glaucoma is statistically lower than the cellular density of 174 control eyes. The decrease in endothelial cell density increases the risk of edematous corneal dystrophy, more specially after surgery (e.g. cataract extraction). The modifications in corneal endothelial cell(More)
Cataract surgery in glaucoma patients remains a controversial subject. Indication of surgery depends on the type and severity of glaucoma. Surgical results depend on: the technique used for cataract extraction (extracapsular or phacoemulsification), the type of filtration procedure (trabeculectomy or deep sclerectomy) as well as of the site of the surgical(More)
PURPOSE To report the effect of an intravitreal injection of 4 mg of crystalline triamcinolone acetonide (Kenacort) as symptomatic treatment of neovascular glaucoma. MATERIAL AND METHODS This clinical study is based on clinical and experimental investigations that examined the tolerability and the angiostatic effect of triamcinolone acetonide. The study(More)
Surgery is the treatment of choice in angle closure glaucoma. Exceptions to this rule are rare. Peripheral iridectomy is the operation in reversible forms: asymptomatic forms, drug normalized attacks without anatomic alterations of the anterior segment, and when both eyes have the same biometry. Trabeculectomy is the treatment of all irreversible forms:(More)
Cataract surgery in glaucoma patients remains a controversial subjects. Indication of surgery depends on a lot of clinical parameters: diagnosis, state, evolution of glaucoma as well as compliance with medical treatment--surgical procedures of cataract and glaucoma--sites of the surgery--use of antifibrosis agents and surgeon's experience. As cataract(More)