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Many distance learning systems claim to be interactive, but few can offer two-way video, on-the-fly interaction, and application sharing. The authors describe the Interactive Remote Instruction system, which links sites over a high-speed intranet. Distance learning — education without a central classroom — has helped busy people obtain college credits or(More)
Prolactin, a pituitary hormone, has been shown to have an active role in the regulation of the immune system. Prolactin receptors have been described on the membrane of lymphocyte cells, and competitive binding to these receptors by cyclosporine and circulating prolactin has been demonstrated. Experimental evidence suggests a synergistic effect of(More)
OBJECTIVE This is a midterm report of a study comparing the clinical performance of CarboMedics and St Jude Medical heart valve prostheses through a projected 10-year period. METHODS Between 1992 and 1996, a total of 485 patients undergoing mechanical valve replacement were prospectively randomly assigned to receive either CarboMedics (n = 234) or St Jude(More)
PURPOSE Static fixation is the standard method for stabilizing the eye during automated perimetry. Kinetic fixation is an alternative for fixation control in which the eye follows a moving target. This study was conducted to evaluate the fixation accuracy of static and kinetic fixation perimetry and to determine their ability to detect the absolute scotoma(More)
In a prospective study of the relative safety and potential benefit of concomitant ketoconazole and cyclosporine after heart transplantation, 15 transplant recipients were followed up for up to 1 year (mean, 10.7 months) after ketoconazole was added to their immunosuppressive regimen of cyclosporine, prednisone, and azathioprine, and these patients were(More)
This paper discusses the software architecture, inter-process communication and the reference implementation of IRI, an Interactive Remote Instruction system for distance learning. IRI is an Internet-based system which integrates continuous multimedia, shared applications and a variety of multiuser collaborative utilities. Internet multicasting is used by(More)
Changes in the ECG ST segment are often observed in patients with myocardial ischaemia. However, non-ischaemic changes in ST level are also common thereby limiting ischaemia detection accuracy. The aim of this study was to devise an algorithm and determine its accuracy in distinguishing between ischaemic and non-ischaemic changes in the ECG ST-segment,(More)