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The gene encoding pro-opiomelanocortin (POMC) presents unique regulatory features. In particular, glucocorticoids inhibit transcription of the POMC gene in the anterior pituitary, but not in the… (More)
The gene encoding pro-opiomelanocortin (POMC) is specifically expressed in two different cell types of the pituitary gland. We have defined the regulatory DNA sequences of the POMC gene that are… (More)
Specific DNA sequence elements which contain binding sites for the glucocorticoid receptor mediate the action of glucocorticoid hormones on gene transcription. In glucocorticoid-inducible genes,… (More)
Glucocorticoid hormones alter transcription of specific genes. Glucocorticoid-stimulated genes have been especially useful in unraveling molecular events responsible for positive gene regulation in… (More)
Four independent mutants were isolated from mutagenized cultures of CHO cells by sib selection on the basis of resistance to a low concentration (2.6 × 10−5M) of BrdU. All four lines were stable, but… (More)
Ce systeme de controle sans contact utilise un micrometre laser a faisceau fin pour mesurer automatiquement les microprofils ou les profils complexes. Un logiciel installe sur PC gere l'operation,… (More)