J. C. del Toro Iniesta

Learn More
Tyrosine nitration in proteins is an important post-translational modification (PTM) linked to various pathological conditions. When multiple potential sites of nitration exist, tandem mass spectrometry (MS/MS) methods provide unique tools to locate the nitro-tyrosine(s) precisely. Electron capture dissociation (ECD) is a powerful MS/MS method, different in(More)
The iodination of proteins remains a useful tool in biochemistry for radiolabelling. However, chemical or enzymatic iodination is difficult to control and can give deleterious polyiodination. Previously, we have shown that electrooxidation with nitrite is a rapid method for the selective nitration of tyrosine residues in proteins. In principle, it should be(More)
We report the direct electrochemistry of cytochrome c at screen printed graphite electrodes which exhibits quasi-reversible voltammetric responses without the need for any chemical or electrochemical pre-treatment, use of mediators or nanomaterials. Through voltammetric studies and X-ray photoelectron spectroscopy (XPS) it is shown that carbonyl and(More)
Recent work has reported the first electroanalytical detection of pindolol using reduced graphene oxide (RGO) modified glassy carbon electrodes [S. Smarzewska and W. Ciesielski, Anal. Methods, 2014, 6, 5038] where it was reported that the use of RGO provided significant improvements in the electroanalytical signal in comparison to a bare (unmodified) glassy(More)
OBJECTIVE To evaluate the usefulness of endoscopic assisted surgery of pituitary adenomas in transesphenoidal surgery, and in surgery of craneopharyngiomas using either minimally invasive approaches to the cranial base or transventricular approaches. MATERIAL AND METHODS We present our preliminary experience in eleven patients operated of sellar region(More)
A multicomputer architecture is proposed in order to achieve high performance in floating point using FPGA devices. This architecture is used in the system prototype of an instrument that carries out a real-time scientific data analysis aboard the ESA's Solar Or biter space mission. A novel method for parallelizing the scientific algorithm in multicore(More)
Brominated anthraquinones can be synthesized directly from bromothiophenes when these are reacted with 1,4-naphthoquinones in the presence of meta-chloroperoxybenzoic acid. The bromoanthraquinones are versatile building blocks in the preparation of arylated anthraquinones and of extended pi-systems with interspersed anthraquinone units.