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Jean Liu is data curator and blog editor at Altmetric LLP, and Euan Adie is the founder. D riven by the development of new tools for measuring scholarly attention, altmetrics constitute a burgeoning new area of information science. It is an exciting time to be involved in the field since there are so many opportunities to contribute in innovative ways. We(More)
IP address lookup at the router is a complex problem. This has been primarily due to the increasing table sizes, growth in traffic rate and high link capacities. In this work we have proposed an algorithm for fast routing lookup with reduced memory utilization and access time. This approach shows significant performance improvement in the average case and(More)
The present study explored a link between spinal 5-HT(7) and adenosine A(1) receptors in antinociception by systemic amitriptyline in normal and adenosine A(1) receptor knock-out mice using the 2% formalin test. In normal mice, antinociception by systemic amitriptyline 3mg/kg was blocked by intrathecal administration of the selective adenosine A(1) receptor(More)
Tramadol, an analgesic used alone or combined with acetaminophen, has a complex mechanism of action involving opioid and amine mechanisms. In this study, we explored the involvement of spinal and peripheral adenosine A1 receptors in antinociception by tramadol, and determined whether spinal serotonin 5-HT₇ receptors were linked to spinal A1 receptor(More)
Acetaminophen (paracetamol) is a widely used analgesic, but its sites and mechanisms of action remain incompletely understood. Recent studies have separately implicated spinal adenosine A(1) receptors (A(1)Rs) and serotonin 5-HT(7) receptors (5-HT(7)Rs) in the antinociceptive effects of systemically administered acetaminophen. In the present study, we(More)
Squire et al. have proposed that trace and delay eyeblink conditioning procedures engage separate learning systems: a declarative hippocampal/cortical system associated with conscious contingency awareness, and a reflexive sub-cortical system independent of awareness, respectively (Clark and Squire, 1998; Smith et al., 2005). The only difference between(More)
Previous studies with prairie voles suggest that the hormone oxytocin is crucial for bond formation - indicated when a partner preference is formed towards the target vole. In this study, we conduct the first empirical test of whether oxytocin likewise promotes partner preferences in humans. Seventy-six undergraduate students received either oxytocin or(More)
Research in animals and humans suggests a role of oxytocin in social approach to strangers. We tested this by introducing undergraduate students to opposite-gendered strangers, with each member of the pair having taken either oxytocin or placebo. One hundred and four undergraduate students were paired up and engaged in a face-to-face conversation structured(More)
BACKGROUND Dietary disinhibition is a behavioral trait associated with weight gain and obesity. Because food choices are made according to the relative value assigned to each option, examination of valuation signals through functional magnetic resonance imaging (fMRI) may elucidate the neural basis for the association between dietary disinhibition and(More)