J. C. Lalanne

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2014 A new method is proposed to measure the curvature elastic modulus kc of a membrane, by observing the thermal induced fluctuations of the shape of a spherical vesicle. Observations of the liposomes were carried out under a microscospe working in the regime of Nomarski differential interference contrast. We show that the value of kc thus measured is the(More)
In solutions of increasing ionic strength, the molecular weight of melittin varies from 2840 (monomeric melittin) to 11200. This polymerization, concomitant with an important change in conformation (Talbot, J.C., Dufourcq, J., De Bony, J., Faucon, J.F. and Lussan, C. (1979) FEBS Lett. 102, 191-193), is accompanied by a significant alteration in the partial(More)
A preparation of cyclosporine A (CsA) in small liposomes (300 nm) was tested in a rat model of heterotopic cardiac allograft. At a daily dose of 1,5 mg/kg during 14 days, the graft survival rate was 30.4 +/- 2.8 days with a liposome-CsA solution versus 16 +/- 2.3 days with a Cremophore-CsA solution (p less than 0.01). Animals treated with the liposome-CsA(More)
Second-harmonic light scattering (SHS) studies of liquid mixtures are shown to provide valuable information regarding correlations between non-centrosymmetric (e. g. dipolar) molecules and centrosymmetric (e. g. quadrupolar) ones, between dipolar molecules and tetrahedral ones, as well as between the components of atomic media. Such studies moreover permit(More)
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